Sunday, May 14, 2023     8:00 AM – 10:00 AM ET     Room 204ABC

Block Symposium

Generously supported by JDRF

T Cell Responses in Autotimmune Disease

Chairs

• Amy Lovett-Racke, Ohio State Univ. Med. Ctr.
• Brian Evavold, Univ. of Utah

Speakers

• Zemin Zhou, Univ. of Utah, DM functions differently in thymic antigen presentation cell subsets in development of autoreactive CD4⁺ T cells
• John P. Driver, Univ. of Missouri, Columbia, Deletion of Vβ3⁺ CD4⁺ T-cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8⁺ T-cells
• Sanya Arshad, Univ. of Pittsburgh, Identification of T cell autoantigens in a mouse model of lupus nephritis
• Christina N. Rau, Ohio State Univ. Wexner Med. Ctr., miRNAs targeting TGFβ-signaling disrupt Treg development and function in CNS autoimmunity
• Samuel J. Connell, Univ. of Iowa, CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease
• Peter A. Morawski, Benaroya Res. Inst., Cutaneous T cells promote distinct outcomes in human skin structural cells associated with inflammatory disease
• Sydney B. Crotts, Mayo Clin. Grad. Sch. of BioMed. Sci., The role of ST8Sia6 in braking inflammation in inflammatory bowel disease
• Ivy L. Debreceni, Univ. of Iowa, IL-27 promotes pathogenic Tfh-like CD4 effectors and exhausted-like CD8 T cells in a mouse model of Sjögren's