Friday, May 12, 2023 12:30 PM – 2:30 PM ET Room 207A
Block Symposium
Express Yourself: Molecular Events in Antigen Presentation
Chairs
- Marlene Bouvier, Univ. of Chicago
- Scheherazade Sadegh-Nasseri, Johns Hopkins Univ.
- Pamela A. Wearsch, Case Western Reserve Univ.
Speakers
- Michael J. Hogan, Children's Hosp. of Philadelphia, Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response
- Jesus Contreras Rodriguez, Johns Hopkins Unic., Decrypting pMHCI diversity through noncanonical translation initiation
- Malini Raghavan, Univ. of Michigan Med. Sch., Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA-I) allotypes
- Marlene Bouvier, Univ. of Illinois Chicago, Visualization and characterization of the elusive MHC I intermediate states by x-ray crystallography and in silico studies
- Adrian Martin-Esteban, John Hopkins Med. Inst., The ER aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities
- Kannan Natarajan, NIAID, NIH, Mechanistic aspects of tapasin-mediated antigen presentation revealed by structure of a tapasin/MHC-I complex
- Viva Jeanne Rase, Univ. of Utah, Human versus mouse Beta 2 microglobulin alters TCR antigen recognition kinetics with mouse MHCI
- Amanpreet Kaur, Univ. of Michigan Med. Sch., Mass spectrometric profiling of HLA-B44 peptidomes provides evidence for Tapasin-mediated Tryptophan editing
