Friday, May 12, 2023 10:15 AM – 12:15 PM ET Room 102AB
Block Symposium
Regulators of Lymphocyte Fate and Activation
Chair
- Jennifer Cannons, NIAID, NIH
Speakers
- Peter Pioli, Univ. of Saskatchewan, Canada, Thymus antibody-secreting cells possess an interferon-responsive gene signature and are comprised of a CD154(CD40L) dependent plasmablast population
- Doureradjou Peroumal, Univ. of Pittsburgh Sch. of Med., Kidney disease impairs B cells response against infection via inhibiting germinal center formation and antibody titers
- Roy Neal Mulpur, Emory Univ. Sch. of Med., CRISPR/Cas9 screen of B cell differentiation pathways
- Marie Pineault, Université Laval, Canada, The mutation PTPN6Ala455Thr causing pulmonary emphysema affects B cell populations and causes spontaneous pulmonary tertiary lymphoid tissue formation
- Michela Locci, Perelman Sch. of Medicine, Univ. of Pennsylvania, IL-12 drives the differentiation of human T follicular regulatory cells
- Dominic P. Golec, NIAID, NIH, PI3Kδ shapes Th2 lineage restriction through coordination of IL-2 signaling, Foxo1 inactivation and epigenetic remodeling
- Danielle Alexandria Chisolm, NIAMS, NIH, PAXBP1 serves as a novel regulator of t helper specification by restraining the type 1 program
- Jessica A. Gaevert, St. Jude Childrens Res. Hosp., Characterization, functional validation, and analysis of the cross-reactive T cell repertoire in the context of heterosubtypic influenza A virus infection
